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. 2019 Jun 28;9:563. doi: 10.3389/fonc.2019.00563

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Copyright © 2019 Larousserie, Kebe, Huynh, Audebourg, Tamburini, Terris and Devergne.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation among GCB or ABC molecular forms of DLBCL between IL-35 expression and either overall survival or expression of IL-10 and co-inhibitory receptors. (A,C) Percentage (y-axis) of overall survival over time (x-axis) (Kaplan-Meier survival curve) of CHOP- or R-CHOP-treated GCB or ABC DLBCL patients from the indicated series, associated with low or high IL-35 expression levels. p-values of log-rank test are indicated. (B,D) Gene expression of the indicated genes among the various molecular forms of DLBCL defined by gene profiling (log2 scale) is shown. Horizontal line indicates the mean (±SD). p-values of student t-tests are indicated. NS, not significant.