Table 2.
Characteristics of children with CPHD (N = 120 884) with and without VTE in the MarketScan Commercial Databases for 2003‐2013
| VTE (n = 957) n (%) | No VTE (n = 119 927) n (%) | P value | |
|---|---|---|---|
| Age (y) | |||
| <1 | 501 (52.4) | 52 969 (44.2) | <0.0001 |
| 1‐4 | 58 (6.1) | 12 134 (10.1) | |
| 5‐9 | 43 (4.5) | 15 364 (12.8) | |
| 10‐14 | 123 (12.9) | 21 380 (17.8) | |
| 15‐17 | 232 (24.2) | 18 080 (15.1) | |
| Mean age (SD) | 6.0 (7.1) | 5.7 (6.3) | 0.27 |
| Male gender | 582 (60.8) | 62 918 (52.5) | <0.0001 |
| Type of CPHDa | |||
| Single‐ventricle physiology | 262 (27.4) | 11 186 (9.3) | <0.0001 |
| Two‐ventricle physiology | 364 (38.0) | 71 836 (59.9) | <0.0001 |
| Cardiomyopathies | 37 (3.9) | 2255 (1.9) | <0.0001 |
| Conduction disorders and dysrhythmias | 291 (30.4) | 34 090 (28.4) | 0.18 |
| Acquired chronic cardiovascular conditions | 101 (10.6) | 5411 (4.5) | <0.0001 |
| In‐hospital mortality | 103 (10.8) | 1582 (1.3) | <0.0001 |
| Co‐occurring conditions and procedures | |||
| Noncardiac complex chronic conditions | 618 (64.6) | 25 815 (21.5) | <0.0001 |
| Neuromuscular | 242 (25.3) | 7093 (5.9) | <0.0001 |
| Respiratory | 165 (17.2) | 5398 (4.5) | <0.0001 |
| Renal | 84 (8.8) | 2207 (1.8) | <0.0001 |
| Gastrointestinal | 79 (8.3) | 2032 (1.7) | <0.0001 |
| Hematology and immunodeficiency | 77 (8.1) | 1699 (1.4) | <0.0001 |
| Metabolic | 93 (9.7) | 2297 (1.9) | <0.0001 |
| Other congenital or genetic defect | 220 (23.0) | 10 183 (8.5) | <0.0001 |
| Malignancy | 153 (16.0) | 3621 (3.0) | <0.0001 |
| Recent trauma | 182 (19.0) | 6502 (5.4) | <0.0001 |
| Recent infection | 370 (38.7) | 9725 (8.1) | <0.0001 |
| Recent noncardiac surgery | 478 (50.0) | 5663 (4.7) | <0.0001 |
| Recent cardiac surgery | 511 (53.4) | 4106 (3.4) | <0.0001 |
| Acquired acute cardiovascular conditions | 123 (12.9) | 1724 (1.4) | <0.0001 |
| Evidence of end‐stage cardiac disease | |||
| Heart transplantation | 4 (0.4) | 1 (0.0) | <0.0001 |
| Extracorporeal membranous oxygenation | 22 (2.3) | 83 (0.07) | <0.0001 |
CPHD, chronic pediatric heart disease; SD, standard deviation; VTE, venous thromboembolism.
a
Categories not mutually exclusive.