Figure 4.

Cognitive reappraisal network influence on the emotional reactivity network during the reappraise condition. (A) The significant group differences illustrated on the brain network illustration and graph visualization. Each region is color-coded according to the t statistic value from the t-test assessing group differences in internetwork influence All pairwise ROIs with connections, significant at the P < 0.05 level, are plotted as edges. (B) The internetwork influence of the cognitive reappraisal network regions on the emotional reactivity regions averaged over all 70 SAD patients and 25 healthy controls. The SAD group showed significantly lower right IFG influence on the emotional reactivity network. (C) In addition, the SAD group exhibited a significantly lower total influence of the reappraisal network on the emotional reactivity network compared with HC.