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. 2019 Jun 28;10:733. doi: 10.3389/fphar.2019.00733

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Copyright © 2019 Gao, Zhao, Wang, Zhang, Zhou, Qu, Wang, Yin, Hong and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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C-phycocyanin attenuated intrinsic apoptosis induced by OGD/R injury in H9c2 cells. (A) The Western blot of endogenous apoptosis pathway proteins and Bax. (B–E) The Western blotting of cytochrome c expression (B), Apaf-1 (C) and procaspase-9 (F), and Bax (E) in H9c2 cells. For detecting protein expression, cells were treated with C-pc (0, 10, 20, and 40 μg/ml) or PBS and subjected to OGD/R expect control group. Data were expressed as mean ± SEM (n = 5). ^# P < 0.05, ^## P < 0.01 versus control (normal) group; *P < 0.05, **P < 0.01 versus C0 (OGD/R model) group.