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. 2019 May 28;6(7):ofz254. doi: 10.1093/ofid/ofz254

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© The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — (A) Invasion antibody profiles of children with malaria across 3 endemic regions of Ghana. Antibody reactivity of malaria-positive children to erythrocyte-binding antigen (EBA) and reticulocyte binding-like homolog proteins (Rh) between Kintampo (N = 167), Navrongo (N = 131), and Accra (N = 125). *, Group means differ significantly (P < .05, Student’s t test). (B) Age-dependent acquisition of immunoglobulin (Ig)G against recombinant EBA and Rh proteins. The IgG reactivity of malaria-positive children (N = 423) to the antigens were grouped to 2 age groups: 2–5 years and 6–14 years. Bars represent group means, and error bars represent standard errors of the means. *, Group means differ significantly (P < .05, Student’s t test). ELISA, enzyme-linked immunosorbent assay; FL, full length; OD, optical density.