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. 2019 Jul 5;14(7):e0218816. doi: 10.1371/journal.pone.0218816

Table 6. Association of body mass index (BMI) percentiles for age classification with cardiometabolic risk factors, age & sex adjusted, at ages 3 and 5 years.

Year 3 Measures Year 5 Measures
Normal Overweight Class I Obese p-value Normal Overweight Class I Obese Class II Obese p-value
N 485 77 36 407 69 31 6
Total Cholesterol mmol/L, mean (SE) 4.03 (0.03) 3.96 (0.09) 4.06 (0.13) 0.71 4.08 (0.04) 4.07 (0.10) 4.14 (0.13) 3.76 (0.32) 0.75
HDL mmol/L, mean (SE) 1.32 (0.01) 1.27 (0.04) 1.38 (0.05) 0.25 1.41 (0.02) 1.44 (0.04) 1.45 (0.06) 1.03 (0.14) 0.04
LDL mmol/L, mean (SE) 2.40 (0.03) 2.38 (0.08) 2.39 (0.11) 0.98 2.35 (0.03) 2.34 (0.09) 2.32 (0.12) 2.18 (0.29) 0.95
Triglycerides mmol/L, mean (SE) 0.69 (0.01) 0.67 (0.04) 0.70 (0.05) 0.85 0.70 (0.02) 0.63 (0.04) 0.80 (0.06) 1.19 (0.14) 0.001
Fasting Glucose mmol/L, mean (SE) 4.46 (0.02) 4.62 (0.05) 4.62 (0.08) 0.005 4.60 (0.02) 4.74 (0.05) 4.73 (0.07) 4.91 (0.16) 0.006
SBP-z, mean (SE) -0.06 (0.12) -0.003 (0.12) 0.40 (0.18) 0.045 -0.11 (0.05) 0.27 (0.13) 0.60 (0.18) 1.22 (0.41) < .0001
DBP-z, mean (SE) -0.06 (0.05) 0.23 (0.12) 0.20 (0.18) 0.047 -0.07 (0.05) 0.07 (0.13) 0.58 (0.19) 0.05 (0.42) 0.008

HDL—High-density lipoproteins, LDL—Low-density lipoprotein, SBP-z—Sex and height adjusted z-scores for systolic blood pressure, DBP-z—Sex and height adjusted z-scores for diastolic blood pressure. Significant differences are indicated in bold.

All analysis were adjusted for age, sex, ethnicity, annual household income, gestational age, maternal smoking during pregnancy, birth weight, and physical activity levels (at 3- and 5-years).