Table 2. Association and dissociation constants for the interaction of purified FSH with FSH receptor.
Sample | kon, nM-1*min-1 | koff, min-1 | t1/2, min | KD, pM |
---|---|---|---|---|
Gonal-F | 0.89±0.23 | 0.0057±0.0017 | 134±40 | 6.3±2.5 |
FSH #1 | 0.71±0.13 | 0.0034±0.0006 | 209±35 | 4.8±1.2 |
FSH #2 | 0.65±0.16 | 0.0043±0.0008 | 167±31 | 6.6±2.1 |
Data are given as mean ± 95% confidence interval, n = 2.