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. Author manuscript; available in PMC: 2019 Jul 5.
Published in final edited form as: J Biomed Mater Res A. 2017 Sep 25;105(12):3392–3399. doi: 10.1002/jbm.a.36186

Fig. 1. Steps in microdrilling agarose scaffolds.

Fig. 1

(a) A sacrificial agarose disk is placed at the bottom of the well of a well-plate. An agarose disk with a height equivalent to the desired height of the scaffold (10 mm in the present study) was placed over the sacrificial layer. (b) A CNC-controlled microdrilling linear channels in the agarose disk. (c) A titanium tube was sharpened to a knife-edge and was used to cut scaffolds. (d) The scaffolds with linear channels were extracted from the sharpened punch.