Table 2.

Univariate and multivariate logistic regression analyses for overall survival of high-grade glioma patients

Characteristic	Univariate			Multivariate
	Odds ratio	95% CI	p-value	Odds ratio	95% CI	p-value
Age	1.012	0.980–1.045	0.475
Gender	0.855	0.566–1.293	0.459
WHO performance status	1.312	0.808–2.130	0.272
Extent of surgery	0.508	0.331–0.778	0.002	0.604	0.380–0.962	0.034
MGMT promoter status	0.154	0.084–0.281	<0.001	0.160	0.085–0.302	<0.001
IDH1 status	0.629	0.466–0.849	0.002	0.885	0.646–1.212	0.47
Baseline NLR	1.150	1.028–1.286	0.014	1.029	0.928–1.141	0.584
NLR decreased	0.474	0.306–0.733	0.001	0.481	0.247–0.934	0.031
NLR increased	1.584	1.064–2.357	0.023	0.678	0.366–1.254	0.215

Note: Univariate variables with P<0.2 were included in the multivariate model.

Abbreviations: IDH1, isocitrate dehydrogenase 1; MGMT，O6-methylguanine–DNA methyltransferase; NLR, neutrophil-to-lymphocyte ratio.