Table 1.
Clinical and tumor characteristics according to the presence of SRC
| Variables | SRC [n = 129] | Non-SRC [n = 560] | p value |
|---|---|---|---|
| Age, years (mean [SD]) | 61.98 [8.44] | 61.53 [9.07] | 0.945 |
| Sex | |||
| Male | 117 (90.7) | 500 (89.3) | 0.636 |
| Female | 12 (9.3) | 60 (10.7) | |
| Tumor location | |||
| Upper esophagus | – | 2 (0.4) | 0.596 |
| Middle | 4 (3.1) | 30 (5.4) | |
| Lower | 70 (54.3) | 309 (55.2) | |
| GO junction | 55 (42.6) | 219 (39.1) | |
| cT stage | |||
| T1 | – | 12 (2.1) | 0.213 |
| T2 | 30 (23.3) | 146 (26.1) | |
| T3 | 92 (71.3) | 373 (66.6) | |
| T4 | 3 (2.3) | 21 (3.8) | |
| Missing | 4 (3.1) | 8 (1.4) | |
| cN stage | |||
| N0 | 60 (46.5) | 253 (45.2) | 0.373 |
| N1 | 50 (38.8) | 219 (39.1) | |
| N2 | 10 (7.8) | 68 (12.1) | |
| N3 | 2 (1.6) | 8 (1.4) | |
| N+ | 1 (0.8) | 1 (0.2) | |
| Nx | 2 (1.6) | 4 (0.7) | |
| Missing | 4 (3.1) | 7 (1.3) | |
| cM stage | |||
| M0 | 107 (82.9) | 475 (84.8) | 0.503 |
| M1 | 7 (5.4) | 28 (5) | |
| Mx | 11 (8.5) | 50 (8.9) | |
| Missing | 4 (3.1) | 7 (1.3) | |
| Neoadjuvant treatment | |||
| nCRT | 65 (50.4) | 326 (58.2) | 0.106 |
| nCT | 64 (49.6) | 234 (41.8) | |
Data are expressed as n (%) unless otherwise specified
SRC signet ring cell, SD standard deviation, GO gastroesophageal, nCRT neoadjuvant chemoradiotherapy, nCT neoadjuvant chemotherapy