Table 4.
Drug | Year of introduction | Country where resistance was first described | Year resistance was first described | Speciesa |
---|---|---|---|---|
Sulphaquinoxaline | 1948 | USA | 1954 | Et |
Nitrofurazone | 1948 | USA | 1955 | Not given |
Nicarbazin | 1955 | Britain | 1964 | Et |
Dinitolmide | 1960 | Britain | 1964 | Et, En |
Amprolium | 1960 | Britain | 1964 | Eb |
Clopidol | 1966 | Britain | 1969 | Ea, Em, Et |
Buquinolate | 1967 | USA | 1968 | Not given |
Methyl benzoquate | 1967 | Britain | 1970 | Et |
Decoquinate | 1967 | Britain | 1970 | Et |
Monensin | 1971 | USA | 1974 | Em |
Robenidine | 1972 | USA | 1974 | Em |
Halofuginone | 1975 | France | 1986 | Ea, Et |
Lasalocid | 1976 | USA | 1977 | Ea |
Arprinocid | 1980 | Britain | 1982 | Et |
Salinomycin | 1983 | USA | 1984 | Various |
Diclazuril | 1990 | Brazil | 1994 | Ea, Em, Et |
Toltrazuril | 1986 | Netherlands | 1993 | Not given |
aSpecies: Ea, E. acervulina; Eb, E. brunetti; Em, E. maxima; En, E. necatrix; Et, E. tenella