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. 2019 Jul 5;9:9758. doi: 10.1038/s41598-019-46193-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Dietary impacts on VFM depend on gut microbiota composition, but the opposite trend does not apply. (a) Significance of the association between VFM and VFM-associated OTUs after correction for 5 nutrients. (b) Variation in the absolute effect size of OTUs on VFM, depending on dietary component adjustment; all results are at FDR < 5% unless noted by n.s. (not significant). (c) Significance of the association between VFM and dietary components after correcting for VFM-associated OTUs relative abundance. (d) Significance of association between VFM and 93 OTUs represented as –log(P-value) while correcting for different dietary components.