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. 2019 Jul 5;9:9743. doi: 10.1038/s41598-019-46286-6

Table 2.

Overall survival and progression free survival Cox univariate analysis.

Covariate HR 95% CI p-value
Progression free survival
Histopathological N = 1 7.8 1.7 to 35.0 0.0076
Stage = 3 11.1 2.1 to 57.9 0.0044
Gene expression ABCC2 (unchanged) 5.0 1.1 to 22.4 0.0354
Radiomic Flatness 0.0003 0.0 to 0.3 0.0234
SENTGLMC R 0.5 0.31 to 0.91 0.0205
EntropyGLMC E 0.046 0.006 to 0.35 0.0031
GLNUL 0.074 0.007 to 0.77 0.0298
Overall survival
Histopathological Stage = 4 3.1 1.1 to 8.6 0.0304
Gene expression ALDH1A1 (up-regulated) 2.8 1.0 to 7.3 0.0420
Radiomic Ratio 3D Surface/volume 3.3 1.2 to 9.2 0.0219
Flatness 0.012 0.0001 to 0.6 0.0275
IDMR 270.1 1.3 to 55079.2 0.0401
IDR 655.3 1.1 to 393927.0 0.0481

HR = hazard ratio. SENT (sum entropy). EntropyGLCM = entropy from grey-level-co-occurrence-matrix. GLNU = grey-level nonuniformity. IDM = Inverse difference moment. ID = Inverse difference.