Table 2.
Covariate | HR | 95% CI | p-value | |
---|---|---|---|---|
Progression free survival | ||||
Histopathological | N = 1 | 7.8 | 1.7 to 35.0 | 0.0076 |
Stage = 3 | 11.1 | 2.1 to 57.9 | 0.0044 | |
Gene expression | ABCC2 (unchanged) | 5.0 | 1.1 to 22.4 | 0.0354 |
Radiomic | Flatness | 0.0003 | 0.0 to 0.3 | 0.0234 |
SENTGLMC R | 0.5 | 0.31 to 0.91 | 0.0205 | |
EntropyGLMC E | 0.046 | 0.006 to 0.35 | 0.0031 | |
GLNUL | 0.074 | 0.007 to 0.77 | 0.0298 | |
Overall survival | ||||
Histopathological | Stage = 4 | 3.1 | 1.1 to 8.6 | 0.0304 |
Gene expression | ALDH1A1 (up-regulated) | 2.8 | 1.0 to 7.3 | 0.0420 |
Radiomic | Ratio 3D Surface/volume | 3.3 | 1.2 to 9.2 | 0.0219 |
Flatness | 0.012 | 0.0001 to 0.6 | 0.0275 | |
IDMR | 270.1 | 1.3 to 55079.2 | 0.0401 | |
IDR | 655.3 | 1.1 to 393927.0 | 0.0481 |
HR = hazard ratio. SENT (sum entropy). EntropyGLCM = entropy from grey-level-co-occurrence-matrix. GLNU = grey-level nonuniformity. IDM = Inverse difference moment. ID = Inverse difference.