Table 3.
Kaplan-Meier analysis and resulting hazard ratios for stratifying patients for OS and PFS using single features identified by the univariate Cox modeling or their combination.
| HR | 95% CI | p-value | |
|---|---|---|---|
| Model Overall survival (OS) | |||
| Ratio 3D Surface/volume | 2.8 | 1.0 to 7.3 | 0.0420 |
| ALDH1A1 | 3.3 | 1.2 to 9.2 | 0.0219 |
| Cox model with Ratio and ALDH1A1 | 8.4 | 3.4 to 20.6 | 0.0005 |
| Model Progression free survival (PFS) | |||
| Stage 3 only | 11.1 | 2.1 to 57.9 | 0.0044 |
| Cox model combining Stage 3 and EntropyGLMC E | 14.2 | 2.4 to 85.3 | 0.0039 |
| Cox model combining Stage 3 and ABCC2 | 15.0 | 2.9 to 77.4 | 0.0007 |
| Cox model combining ABCC2 and EntropyGLMC E | 14.8 | 2.9 to 76.2 | 0.0008 |
| Cox model combining Stage 3, ABCC2 and EntropyGLMC E | 22.8 | 3.7 to 141 | <0.0001 |