Table 1.
Compound | Final concentration | Solvent |
---|---|---|
GSK621 | 10 µMa | DMSO |
Metformin | 1 mM, 5 mM,10 mM | DMEM |
Nintedanib | 1 µMa | DMSO |
Noggin | 200 ng/mL | Noggin reconstitution buffer |
Pirfenidone | 0.3 mg/mLa | Ethanol |
Selumetinib | 5 µMa | DMSO |
rhTGFβ1 | 2 ng/mL | rhTGFβ1 reconstitution buffer |
rhBMP2 | 50 ng/mLa | rhBMP2 reconstitution buffer |
aDosage was chosen based on a literature search and the dose showing highest efficacy was selected