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Families display intrafamilial disease discordance regardless of responsible underlying mutation type. Each vertical line represents 1 family with intrafamilial discordance, and each dot represents a single patient. Filled dots represent age at end-stage renal disease (ESRD), and empty circles are age of censor (death or last follow-up with renal sufficiency). IF, in-frame insertion/deletion; NT, nontruncating; PT, protein-truncating.
