Table 1.

Anatomical and quantitative MRI acquisition details. Axial scans were centered at the level of the C2/C3 disc, which provided full coverage of the C2 and C3 cord levels and partial coverage of C1 and C4. Resolution (RES) and field of view (FOV) values correspond to the Left-Right, Ventral-Dorsal, and Inferior-Superior directions. (TE = Echo time, TR = Repetition time, TSE = Turbo spin echo, FA = Flip angle, SENSE = Sensitivity encoding).

Anatomical	Quantitative
Sagittal T2-Weighted •2D Multi-slice •TR/TE: 3000/120 ms •TSE Factor: 24 •FA: 90° •RES: 0.8x1x3mm •FOV: 160x250x36 mm •Time: 3 min	Myelin Water Imaging 3D Multi-echo Gradient and Spin Echo (GRASE) •Axial orientation, 16 slices •32 Echoes •TR/TE: 1500/10 ms •RES: 0.75x0.75x5mm •FOV: 180x150x40mm •Time: 8 min 36 s	Quantitative T1 3D Spoiled Gradient Recalled •Axial orientation, 14 slices •TR/TE: 5.5/2.7 ms •SENSE Factor: 2 •FA: 2,3,4,6,8,13,18° •RES: 0.75x0.75x4 mm •FOV: 180x200x56 mm •Time: 7x11 s = 1 min 17s
Multi-Echo Gradient Echo •2D Multi-slice •Axial orientation, 16 slices •TR/TE1/TE2–5: 815/6.6/8.2 ms •RES: 0.8x0.8x2.5 mm •FOV: 150x150x43.75 mm •Time: 5 min	Diffusion Tensor Imaging •Axial orientation, 10 slices •B-values: 0 & 750 •32 directions •TR/TE = 3362/68 ms •RES:1x1x5mm •FOV: 64x64x52mm •Time: 4 min 42 s	Quantitative T1 3D Inversion Recovery Spoiled Gradient Recalled •Axial orientation, 14 slices •TR/TE/TI: 5.5/2.7/350 ms •SENSE Factor: 2 •FA: 5° •RES: 0.75x0.8x8mm •FOV: 180x200x56 mm •Time: 17 s