Table 3.
Adjusted Associations With Cortisol Diurnal Dynamic Range and AUC—Results of Full Models; Study of Midlife in the United States
| Dynamic range (log nmol/L) | AUC (log(nmol/L)-hr) | |
|---|---|---|
| Estimate (95% CI) | Estimate (95% CI) | |
| Age (per decade) | −0.048 (−0.066, −0.031)*** | 0.11 (0.09, 0.14)*** |
| Gender: men | −0.023 (−0.064, 0.018) | 1.43 (0.89, 1.98)*** |
| Race/ethnicity: not white | −0.296 (−0.355, −0.237)*** | −0.15 (−0.95, 0.64) |
| Education: high school or less | −0.087 (−0.139, −0.035)** | −0.44 (−1.14, 0.26) |
| some college | −0.052 (−0.102, −0.003)* | −0.34 (−1.01, 0.33) |
| FIPR, adult | 0.003 (−0.002, 0.008) | −0.01 (−0.07, 0.06) |
| Social strain, adult (0–3) | −0.053 (−0.098, −0.007)* | 0.18 (−0.43, 0.79) |
| Total early-life adversity (0–6) | −0.018 (−0.039, 0.002)# | 0.00 (−0.27, 0.28) |
Note: AUC = area under the log-cortisol curve; CI = confidence interval; FIPR = family size adjusted income to poverty ratio. Associations are from results of mixed effects models with dynamic range and AUC as dependent variables (in separate models), and include a random intercept at the family level. Sample size: 1,606 (from 1,335 families). Reference groups: women (for gender), non-Hispanic white (for race/ethnicity), Bachelor’s degree (for education).
# p < .1. *p < .05. **p < .005. ***p < .0001.