Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 5;21:78. doi: 10.1186/s13058-019-1154-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — The effect of MK-2206 on signaling in PBMC and PRP samples. Differences between baseline and post-treatment expression of pAKT-T308, pAKT-S473, pS6 S235/236 and pS6 S240/244 with two-sided t test. P < .05 was considered statistically significant. a Upper panel—platelets: group 1: early and C1D1: post-treatment, early and C1D2 for 15 patients who have early samples available. Group 2: C1D1:pre-treatment and C1D1: post-treatment, C1D1:pre-treatment and C1D2 for 13 patients who have C1D1:pre-treatment available. Lower panel—PBMC: group 1: early and C1D1:post-treatment, Early and C1D2 for 15 patients who have early samples available Group 2: C1D1:pre-treatment and C1D1:post-treatment, C1D1:pre-treatment and C1D2 for 13 patients who have C1D1:pre-treatment available. b Tumor