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. 2019 Jul 6;7:102. doi: 10.1186/s40168-019-0717-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Canonical correlations between historic sample proteins and metabolites. The strongest canonical correlations in historic calculus are presented as network graphs where the nodes are proteins/metabolites and edges represent canonical correlations, with darker, thinner lines lower values and thicker, lighter lines higher values. Nodes are sized by the number of edges they have and are colored based protein on metabolite category. a Bacterial and human protein correlations ≥ 0.9. b All protein and metabolite correlations ≥ 0.9. Graphs with node names are included in Additional file 1: Figures S18-S19