Table 1.
Demographic data for the early RA cohort (ARCTIC cohort) and the established RA cohort (ULRABIT cohort) and in combination
| ARTIC cohort | ULRABIT cohort | Combined cohort | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variable | N | Median | 25 percentile | 75 percentile | N | Median | 25 percentile | 75 percentile | N | Median | 25 percentile | 75 percentile | Min | Max |
| Age | 230 | 53.9 | 41.7 | 62.5 | 212 | 53.2 | 42.05 | 61.45 | 442 | 53.6 | 42 | 62.1 | 18 | 86 |
| Female sex, n (%) | 230 | 141 | 61.3% | 212 | 171 | 80.7% | 442 | 312 | 70.6% | |||||
| Right hand dominance, n (%) | 230 | 212 | 92.2% | 201 | 198 | 98.5% | 431 | 410 | 95.1% | |||||
| Right hand SJC, n (%) | 162 | 90 | 55.6% | 152 | 93 | 61.2% | 314 | 183 | 58.3% | |||||
| Positive anti-CCP, n (%) | 230 | 186 | 80.9% | 211 | 164 | 77.7% | 441 | 350 | 79.4% | |||||
| Positive RF, n (%) | 230 | 164 | 71.3% | 209 | 147 | 70.3% | 439 | 311 | 70.8% | |||||
| Disease duration (months) | n.a. | n.a. | n.a. | n.a. | 212 | 97.1 | 35.7 | 173.5 | 212 | 97.1 | 35.7 | 173.5 | 0.7 | 480 |
| Symptom duration (days) | 230 | 5.6 | 2.8 | 10.2 | n.a. | n.a. | n.a. | n.a. | 230 | 5.6 | 2.8 | 10.2 | 0 | 23.9 |
| SJC28 | 230 | 6 | 3 | 11 | 210 | 5 | 2 | 10 | 440 | 5 | 3 | 10 | 0 | 26 |
| TJC28 | 230 | 6 | 3 | 11 | 210 | 4 | 1 | 9 | 440 | 6 | 2 | 10 | 0 | 28 |
| ESR | 229 | 20 | 11 | 32 | 209 | 25 | 13 | 39 | 438 | 22 | 12 | 35 | 1 | 113 |
| CRP | 230 | 7 | 3 | 18 | 209 | 6 | 2 | 14 | 439 | 7 | 3 | 16 | 0.3 | 126 |
| Doctors Global VAS | 229 | 36 | 23 | 55 | 205 | 28 | 20 | 40 | 434 | 33 | 22 | 48 | 0 | 93 |
| Patient Global VAS | 230 | 49.5 | 31 | 70 | 209 | 50 | 29 | 73 | 439 | 50 | 29 | 71 | 0 | 100 |
| Ultrasound scoring: Baseline | ||||||||||||||
| GS sum score in right hand | 225 | 5 | 2 | 9 | 212 | 7 | 4 | 13 | 437 | 6 | 3 | 11 | 0 | 30 |
| GS sum score in left hand | 225 | 5 | 2 | 8 | 212 | 6 | 3 | 12 | 437 | 6 | 2 | 10 | 0 | 30 |
| Doppler sum score in right hand | 225 | 3 | 0 | 7 | 212 | 3 | 1 | 8 | 437 | 3 | 1 | 7 | 0 | 26 |
| Doppler sum score in left hand | 225 | 2 | 0 | 5 | 212 | 3 | 1 | 7 | 437 | 2 | 0 | 6 | 0 | 25 |
| GLOESS score in right hand | 225 | 5 | 2 | 10 | 212 | 7 | 4 | 13 | 437 | 7 | 3 | 12 | 0 | 30 |
| GLOESS score in left hand | 225 | 5 | 2 | 9 | 212 | 6 | 3 | 12 | 437 | 6 | 2 | 10 | 0 | 30 |
| Ultrasound scoring: 3 months from baseline | ||||||||||||||
| GS sum score in right hand | 116 | 0 | 0 | 2 | 179 | 5 | 3 | 11 | 295 | 3 | 0 | 8 | 0 | 28 |
| GS sum score in left hand | 116 | 0 | 0 | 2 | 179 | 4 | 2 | 9 | 295 | 2 | 0 | 7 | 0 | 27 |
| Doppler sum score in right hand | 116 | 0 | 0 | 0 | 179 | 2 | 0 | 5 | 295 | 0 | 0 | 4 | 0 | 23 |
| Doppler sum score in left hand | 116 | 0 | 0 | 0 | 179 | 2 | 0 | 5 | 295 | 0 | 0 | 3 | 0 | 24 |
| GLOESS score in right hand | 116 | 0 | 0 | 2,5 | 179 | 6 | 3 | 11 | 295 | 3 | 0 | 8 | 0 | 28 |
| GLOESS score in left hand | 116 | 0 | 0 | 2 | 179 | 4 | 2 | 9 | 295 | 2 | 0 | 7 | 0 | 27 |
SJC swollen joint count, TJC tender joint count, ESR erythrocyte sedimentation rate, CRP C-reactive protein, VAS visual analogue scale, GS grey-scale, GLOESS OMERACT-EULAR combined scoring system