Table 1.
HC (n:6) | EtOH (n:6) | TEt-20 (n:6) | TPG (n:6) | p | |
---|---|---|---|---|---|
sIL-1β | 3.60 ± 0.35b,c | 8.15 ± 0.35a,c,d | 4.23 ± 0.48a,b,d | 3.83 ± 0.36b,c | 0.001 |
sTNF-α | 2.85 ± .018b,c | 6.53 ± 0.41a,c,d | 3.51 ± 0.31a,b,d | 3.08 ± 0.194b,c | 0.001 |
sMDA | 1.75 ± 0.18b,c | 4.78 ± 0.19a,c,d | 2.21 ± 0.27a,b,d | 1.58 ± 0.24b,c | 0.001 |
sGSH | 5.91 ± 0.26b,c | 1.61 ± 0.33a,c,d | 5.16 ± 0.16a,b,d | 6.31 ± 0.33b,c | 0.001 |
HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, s serum. a: statistically significantly different compared with HC; b: statistically significantly different compared with EtOH; c: statistically significantly different compared with TEt-20; d: statistically significantly different compared with TPG. (Statistical significance was set at p < 0.05)