Table 2.
HC (n:6) | EtOH (n:6) | TEt-20 (n:6) | TPG (n:6) | p | |
---|---|---|---|---|---|
tIL-1β | 2.18 ± 0.19b,c | 4.98 ± 0.37a,c,d | 2.71 ± 0.19a,b,d | 2.51 ± 0.21b,c | 0.001 |
tTNF-α | 1.10 ± 0.12b,c | 3.21 ± 0.23a,c,d | 1.70 ± 0.14a,b,d | 1.38 ± 0.13b,c | 0.001 |
tMDA | 0.95 ± 0.03b,c | 3.31 ± 0.27a,c,d | 1.35 ± 0.18a,b,d | 0.92 ± 0.03b,c | 0.001 |
tGSH | 4.91 ± 0.24b,c | 1.41 ± 0.36a,c,d | 4.10 ± 0.31a,b,d | 5.30 ± 0.34b,c | 0.001 |
HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, t tissue. HC Healthy controls, EtOH ethanol group, TEt-20 ethanol + thiamine pyrophosphate group, TPG thiamine pyrophosphate group. MDA Malondialdehyde, GSH total glutathione, IL-1β interleukin 1 beta, TNF-α tumor necrosis factor alpha, s serum. a: statistically significantly different compared with HC; b: statistically significantly different compared with EtOH; c: statistically significantly different compared with TEt-20; d: statistically significantly different compared with TPG. (Statistical significance was set at p < 0.05)