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. 2019 Jul 5;20:140. doi: 10.1186/s12931-019-1091-1

Table 4.

Incidence and severity of bleeding related to patient characteristics*

Technique
Cryobiopsy (N = 359) Forceps biopsy (N = 359)
Bleeding severity None/Mild Moderate/Severe p-value None/Mild Moderate/Severe p-value
Clinical relevance Low High Low High
all – no (%) 301 (83.8) 58 (16.2) 344 (95.8) 15 (4.2)
n
Age 349
  < 65 yr 160 143 17 0.018 155 5 0.59
  > = 65 yr 189 151 38 180 9
Sex 351
 Female 153 121 32 0.026 145 8 0.41
 Male 198 175 23 192 6
Body height 342
  = <  170 cm 186 146 40 0.002 175 11 0.043
  > 170 cm 156 142 14 154 2
Smoking 332
 Non-smoker 132 109 23 0.52 124 8 0.27
 Ex-smoker 138 118 20 135 3
 Current smoker 62 55 7 59 3
Aspirin 354
 Yes 51 38 13 0.067 49 2 1.0
 No 303 258 45 290 13

*Clinical relevance of bleeding is categorized as “low” (none, and mild bleeding) and “high” (moderate and severe bleeding) for both biopsy techniques. Absolute number (n) of evaluable patients are listed in the second column. Data were missing for age in 10 patients (2.8%), sex in 8 patients (2.2%), body height in 17 patients (4.7%), smoking status in 27 patients (7.5%), and for aspirin use in 5 patients (1.4%). P-values were calculated by 2 tail Fisher’s exact test for independent samples focusing on each technique separately