Table 5.
Blood pressure and nephropathy indices measured at baseline and 12 weeks after the intervention in subjects who received either Crocus sativus or placebo
| Variables | Crocus sativus groupa (n=40) | p-valueb | Placebo groupc (n=40) | p-valueb | p-valued | ||
|---|---|---|---|---|---|---|---|
| Baseline | After | Baseline | After | ||||
| SBP (mmHg) | 132.7±21.3 | 124.5±13.2 | 0.004 | 127.4±15.3 | 128.3±12.4 | 0.604 | 0.005 |
| DBP (mmHg) | 79.5±10.8 | 76.7±9.9 | 0.104 | 79.7±11.1 | 75.9±14 | 0.091 | 0.621 |
| Serum creatinine (mg/dl) |
1.09±0.17 | 1.1±0.2 | 0.430 | 1.1±0.19 | 1.1±0.2 | 0.964 | 0.505 |
| Serum urea (mg/dl) | 32.6±8.6 | 30.4±8.5 | 0.067 | 31.4±7.4 | 31.2±7.7 | 0.817 | 0.24 |
| Baseline | After | p-valuef | Baseline | After | p-valuef | p-valuee | |
| Albumin (mg/24 hr) | 38.4±22.8 | 35.7±26.7 | 0.332 | 29.8±26.7 | 29.9±25.4 | 0.828 | 0.401 |
Abbreviations: SBP, Systolic blood pressure; DBP, Diastolic blood pressure.
a
Received 100 mg C. sativus per day during the study.
b
As assessed by paired-samples t test.
c
Received 100 mg placebo per day during the study.
d
As assessed by independent-samples t test.
f
As assessed by Wilcoxon signed rank test.
e
As assessed by Mann-Whithney U test.