Table 6.
Adjusted changes in the liver functional tests, blood pressure and nephropathy indices measurement in subjects who received either Crocus sativus or placebo
| Variables |
Crocus sativus groupa (n=40) |
Placebo groupb (n=40) |
p-valuec |
|---|---|---|---|
| AST (U/L) | -1.2±6.6 | -2.3±5.9 | 0.326 |
| ALT (U/L) | -1.3±8.3 | -2.8±8.6 | 0.522 |
| ALP (U/L) | -4.8±37.1 | -0/7±28.1 | 0.858 |
| SBP (mmHg) | -7.2±14.6 | 0.8±9.9 | 0.006 |
| DBP (mmHg) | -2.7±10.3 | -3.8±10.2 | 0.631 |
| Serum creatinine (mg/dl) |
0.02±0.18 | -0.001±0.13 | 0.583 |
| Serum urea (mg/dl) | -2.25±7.54 | -0.27±7.3 | 0.334 |
| Albumin (mg/24 hr) | -0.65±7.01 | 0.05±5.8 | 0.585 |
Abbreviations: AST, Aspartate Aminotransferase; ALT, Alanine Aminotransferase; ALP, Alkaline phosphatase; SBP, systolic blood pressure; DBP, diastolic blood pressure. All values are expressed as means±SD.
a
Received 100 mg C. sativus per day during study.
b
Received 100 mg placebo per day during the study.
c
As assessed by AVCOVA test.