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Tet2 depletion tends to favor ink4a loss of expression. qRT-PCR analysis of Tet2 and cell-cycle inhibitor gene transcripts performed on melanoma biopsies from Tet2+/+, Tet2lox/+, and Tet2lox/lox mice sharing the Tyr::NrasQ61K/°; Tyr::Cre; Ink4a+/− background. The Hprt housekeeping gene was used for normalization.
