Table 1.

Choice of basal insulin and GLAs in special populations

Population	Special concern	Choice of BI	Titration	Additional GLAs
Fasting/Ramadan	Hypoglycemia	Gla-100/Gla-300/degludec	Slow	DPP4i/TZD/glipizide/repaglinide
Pregnancy	Safety	NPH/Detemir/Glargine	Early titration until target	Metformin
Elderly	Hypoglycemia	Gla-100/Gla-300/degludec	Slow/weekly	DPP4i/metformin/SU

BI basal insulin, DPP4i dipeptidyl peptidase-4 inhibitor, NPH neutral protamine Hagedorn, GLA oral glucose-lowering agents, TZD thiazolidinediones, SU sulfonylureas