Table 2.

Potentials of different variables to discriminate between the MODY subtypes and T1D

Variables	T1D vs. MODY 2		T1D vs. MODY 3		MODY 2 vs. MODY 3
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
HbA1c%	0.16 (0.04–0.61)	0.007	0.81 (0.60–1.09)	0.169	2.94 (1.15–7.56)	0.025
Fasting glucose (mmol/L)	0.69 (0.52–0.91)	0.009	0.94 (0.76–1.15)	0.526	1.57 (0.97–2.54)	0.069
2-h glucose (mmol/L)	0.58 (0.42–0.80)	0.001	0.94 (0.82–1.08)	0.375	1.47 (1.02–2.12)	0.039
ln(fasting C-peptide) (ng/mL)	870 (10.6–(7.2×104))	0.002	5.7×104 (1.9–(1.7×109))	0.037	2.31 (0.50–10.80)	0.287
ln(2-h C-peptide) (ng/mL)	2.7×104 (0.5–(1.4×109))	0.065	17.6 (2.0–152)	0.009	0.19 (0.03–1.13)	0.067
lnCRP (mg/dL)	0.48 (0.25–0.94)	0.033	0.19 (0.04–0.95)	0.043	0.21 (0.05–0.86)	0.031
Total cholesterol (mmol/L)	0.37 (0.16–0.89)	0.025	0.81 (0.32–2.04)	0.650	1.70 (0.65–4.45)	0.277
Triglyceride (mmol/L)	0.30 (0.04–2.08)	0.224	8.14 (0.86–77.50)	0.068	12.47 (1.64–94.80)	0.015
HDL-C (mmol/L)	3.85 (0.73–20.48)	0.113	1.48 (0.28–7.71)	0.641	0.14 (0.01–2.04)	0.149
LDL-C (mmol/L)	0.36 (0.14–0.92)	0.032	0.91 (0.36–2.35)	0.852	1.98 (0.70–5.64)	0.200

The OR (95% CI) and P values shown are from logistic regression and have been adjusted for age and gender

Values in bold are significant at P < 0.05

T1D type 1 diabetes, MODY 2 maturity-onset diabetes of the young type 2, MODY 3 maturity-onset diabetes of the young type 3, hs-CRP high-sensitivity C-reactive protein, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol