Table 2.

Potential reasons for switching from another basal insulin to degludec

Common reasons for switching to degludec
To reduce the risk of hypoglycemia
To permit setting of lower glycemic targets considering the risk of hypoglycemia
To provide more stable overnight glucose control because of variable and unpredictable fasting plasma glucose levels, or other indications of glucose variability with a previous basal insulin
To address issues with adherence because of the inflexibility of a previous regimen or the injection process/device
To reduce number of basal injections to simplify the lives of children and caregivers
Allergic reactions to other basal analogs