Table 3.
Univariate analysis of parameters in patients with cumulative oral morphine consumption ≤50 mg and > 50 mg during the first postoperative 72 h
| Cumulative morphine at D3 | ≤ 50 mg (n = 40) | > 50 mg (n = 19) | P |
|---|---|---|---|
| Age > 40 years old | 11 (28%) | 7 (36.8) | 0.46 |
| Gender (male) | 31 (78%) | 13 (68.4) | 0.45 |
| ASA class > I | 14 (35%) | 5 (26.3) | 0.50 |
| BMI (kg.m−2) | 21 [19–23] | 21 [18–22] | 0.88 |
| Preoperative chest tube > 24 h | 26 (65%) | 15 (79%) | 0.27 |
| Hypertension | 4 (10%) | 1 (5%) | 0.54 |
| Diabetes mellitus | 1 (3%) | 0 (0%) | 0.48 |
| Respiratory comorbidity | 0.65 | ||
| Asthma | 3 (8%) | 1 (5%) | |
| COPD | 3 (8%) | 0 (0%) | |
| Interstitial lung disease | 1 (3%) | 0 (0%) | |
| Emphysema | 1 (3%) | 1 (5%) | |
| Past history of pneumothorax | 11 (28%) | 6 (32%) | 0.74 |
| Cannabis chronic use | 12 (30%) | 7 (37%) | 0.59 |
| Single-port incision | 38 (95%) | 16 (84%) | 0.16 |
| Chemical pleurodesis | 32 (80%) | 14 (74%) | 0.58 |
| Pulmonary resection | 23 (58%) | 13 (68%) | 0.42 |
| Postoperative chest tube duration > 1 day | 4 (10%) | 1 (5%) | 0.54 |
| Duration of surgery > 60 min | 21 (53%) | 13 (68%) | 0.24 |
| Anesthetic and analgesic agents | |||
| Total dose of sufentanil used (μg/kg) | 0.89 [0.69–1.11] | 0.81 [0.71–1.22] | 0.76 |
| Ketamine | 31 (78%) | 15 (79%) | 0.90 |
| Intravenous Lidocaine | 26 (65%) | 11 (58%) | 0.59 |
| Dexamethasone | 38 (95%) | 17 (90%) | 0.43 |
| Acetaminophen | 40 (100%) | 19 (100%) | – |
| Nefopam | 39 (98%) | 18 (95%) | 0.58 |
| Ketoprofen | 22 (55%) | 11 (58%) | 0.83 |
| Tramadol | 39 (98%) | 17 (90%) | 0.19 |
| Loco-regional analgesic technique | |||
| Systemic analgesia alone | 6 (15%) | 9 (47%) | 0.02 |
| Paravertebral catheter | 6 (15%) | 3 (16%) | 0.93 |
| Serratus single injection | 12 (30%) | 4 (21%) | 0.47 |
| Serratus catheter | 16 (40%) | 3 (16%) | 0.06 |
Values are expressed as median [25e-75e percentiles] or n (%)
COPD: chronic obstructive pulmonary disease