Table 3.
Urine Sex | Baseline (M ± SD) | 6 months (M ± SD, % changea) | 9 months (M ± SD, % changea) | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Hormones | DEEM | Control | pb,d | DEEM | Control | pc,d | DEEM | Control | pc,d | |
Urine E1, ng/dl | 1.1 ± 0.1 | 2.9 ± 0.2 | .212 | 2.6 ± 0.3 (73.3%) | 1.3 ± 0.2 (−55.2%) | .035 | 1.5 ± 1.1 (36.4%) | 2.5 ± 2.0 (−13.8%) | .253 | |
Urine E2, ng/dl | 1.6 ± 0.1 | 1.1 ± 0.8 | .365 | 1.9 ± 0.1 (20.3%) | 1.0 ± 0.1 (−9.9%) | .085 | 1.6 ± 1.6 (6.4%) | 1.3 ± 1.6 (24.8%) | .140 | |
A-dione, ng/dl | 47.1 ± 4.3 | 62.9 ± 6.0 | .622 | 48.3 ± 4.8 (2.5%) | 54.2 ± 3.4 (−13.8%) | .808 | 65.1 ± 6.0 (38.3%) | 54.2 ± 3.4 (−13.8%) | .685 | |
DHEA, ng/dl | 323.6 ± 33.7 | 97.2 ± 3.3 | .215 | 42.4 ± 3.5 (−87%) | 60.4 ± 3.2 (−38.0%) | .462 | 190.1 ± 2.5 (−137.6%) | 60.4 ± 3.2 (−38.0%) | .626 | |
T, ng/dl | 2.0 ± 0.2 | 3.6 ± 0.3 | .305 | 2.20 ± 0.2 (10.0%) | 2.9 ± 0.3 (−19.0%) | .935 | 3.1 ± 0.3 (31%) | 2.0 ± 0.2 (−19.4%) | .935 |
Note. M = mean; SD = standard deviation.
A-dione = androstenedione; DHEA = dehydroepiandrosterone; E1 = estrone; E2 = estradiol; T = testosterone.
% changes from mean at baseline to each time point (at 6 months and at 9 months).
Testing the differences of baseline between DEEM intervention and control groups.
Testing the differences of changes in urine sex hormones from baseline to each time point (at 6 months and at 9 months) between DEEM and control groups, controlling for baseline sex hormones.
p < 0.05, p-values were determined with rank-transformation using a Kruskal-Wallis test.