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. 2019 Jul 8;6:22. doi: 10.1186/s40580-019-0192-3

Table 2.

Extracted drug s.c. absorption parameters

Peptide FUD 10K PEG-FUD 20K PEG-FUD 40K PEG-FUD mFUD 10K PEG-mFUD 20K PEG-mFUD 40K PEG-mFUD
MW (kDa) 6.0 16.9 27.4 49.6 6.0 16.9 27.4 49.6
t1/2 (hrs) 0.81 3.28 6.77 10.09 0.86 3.06 5.25 8.36
k (s−1) 0.881 0.262 0.160 0.174 0.853 0.323 0.196 0.174
FSC, 24 h (%) 0.6 (± 0.1) 1.47 (± 0.09) 4. (± 1) 10. (± 3) 0.00 (± 0.04) 0.43 (± 0.05) 1.9 (± 0.3) 7. (± 2)