Table 2.
Peptide | FUD | 10K PEG-FUD | 20K PEG-FUD | 40K PEG-FUD | mFUD | 10K PEG-mFUD | 20K PEG-mFUD | 40K PEG-mFUD |
---|---|---|---|---|---|---|---|---|
MW (kDa) | 6.0 | 16.9 | 27.4 | 49.6 | 6.0 | 16.9 | 27.4 | 49.6 |
t1/2 (hrs) | 0.81 | 3.28 | 6.77 | 10.09 | 0.86 | 3.06 | 5.25 | 8.36 |
k (s−1) | 0.881 | 0.262 | 0.160 | 0.174 | 0.853 | 0.323 | 0.196 | 0.174 |
FSC, 24 h (%) | 0.6 (± 0.1) | 1.47 (± 0.09) | 4. (± 1) | 10. (± 3) | 0.00 (± 0.04) | 0.43 (± 0.05) | 1.9 (± 0.3) | 7. (± 2) |