Table 2.
DTC Tests Ordered and DTC Testing Motivations
| Variable | Overall | All Tool Users | Non-health Only Tools | Crossover | Health Only Tools | Test Statistica | p Valuea |
|---|---|---|---|---|---|---|---|
| Number of respondents | 1,137 | 820 | 263 | 458 | 98 | ||
| DTC Tests Ordered (%) | |||||||
| 23andMe | 62.4 | 61.7 | 40.7 | 68.1 | 87.8 | 85.3 | <2.2e−16 |
| AncestryDNA | 53.9 | 59.8 | 73.0 | 62.0 | 14.3 | 104.5 | <2.2e−16 |
| FamilyTreeDNA | 26.8 | 30.2 | 37.3 | 32.1 | 3.1 | 41.2 | 1.14e−09 |
| Rating of DTC Testing Motivationsb(% Very Important) | |||||||
| General curiosity | 68.0 | 67.6 | 55.5 | 71.4 | 82.7 | 30.7 | 2.1e−07 |
| Ancestry | 66.0 | 66.3 | 69.6 | 69.8 | 41.2 | 31.1 | 1.8e−07 |
| Find relatives | 46.9 | 49.9 | 62.4 | 50.4 | 14.3 | 66.1 | 4.4e−15 |
| Risk for specific diseases | 31.4 | 30.9 | 16.1 | 34.2 | 54.1 | 53.9 | 1.97e−12 |
| Limited family health history | 20.7 | 20.7 | 21.4 | 21.0 | 17.7 | 0.621 | 0.733 |
| Other family members are using | 10.7 | 10.7 | 10.8 | 11.0 | 8.3 | 0.656 | 0.720 |
| Participate in research | 32.3 | 31.6 | 26.3 | 33.8 | 34.7 | 4.79 | 0.0911 |
| Raw genetic data file | 50.8 | 53.1 | 44.4 | 56.4 | 60.4 | 11.9 | 0.00263 |
Comparisons of DTC tests ordered and DTC testing motivations, overall and grouped by type(s) of tools used.
a
Comparing non-health only tool users, crossover tool users, and health-only tool users. Test statistics and p values are from chi-square tests.
b
Responses to DTC testing motivations were dichotomized into “very important” versus “somewhat important” or “not at all important.”