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. Author manuscript; available in PMC: 2020 Nov 21.
Published in final edited form as: J Theor Biol. 2019 Jan 5;481:28–43. doi: 10.1016/j.jtbi.2019.01.005

Figure 7: The s2c2 phase-plane trajectory (with nullclines) for the auxiliary reaction mechanism (47)(48).

Figure 7:

The thick black curve is the numerically-integrated solutions to the mass action equations (49a)(49d). The broken red curve is the c2-nullcline, and the broken blue curve is the fixed s2-nullcline (Ns2max, given by (56)). The phase–plane trajectory initially moves towards Ns2max, then moves up Ns2max before moving back down the c2-nullcline. The constants (without units) used in the numerical simulation are: e10=1, s10=1000, k1 = 1, k2 = 1, k3 = 1, k−3 = 1, k4 = 2, e20=100 and k−1 = 1. Curves were scaled by their numerically obtained maximum values.