The thick black curve is the numerically-integrated solutions to the mass action equations (49a)–(49d). The broken red curve is the c2-nullcline, and the broken blue curve is the fixed s2-nullcline (, given by (56)). The phase–plane trajectory initially moves towards , then moves up before moving back down the c2-nullcline. The constants (without units) used in the numerical simulation are: , , k1 = 1, k2 = 1, k3 = 1, k−3 = 1, k4 = 2, and k−1 = 1. Curves were scaled by their numerically obtained maximum values.