Gene arrangement and distribution of the Burkholderia T6SS‐1 gene cluster. Schematic representation of the Burkholderia T6SS‐1 gene cluster and related gene clusters in members of the Proteobacteriaceae. The box shows the genetic organization of the archetype Burkholderia T6SS‐1 gene cluster harbored by the indicated species, including B. cenocepacia (for reference, the B. cenocepacia T6SS‐1 gene cluster corresponds to BCAL0337‐BCAL0353 in strain J2315 and I35_RS01700‐I35_RS01780 in H111, as indicated). Variations on the same basic theme found in other members of the Burkholderia, related genera within the β‐proteobacteria (Achromobacter, Paraburkholderia, Ralstonia, and Rubrivivax), and some members of the γ‐proteobacteria (Acinetobacter, Xanthomonas) are shown