Table 2:
Summary of samples with individual DSM-IV AD criteria in all datasets.
| AA | EA | |||||
|---|---|---|---|---|---|---|
| DSM-IV AD criterion number |
Criterion description |
Sample | # Case | # Control | # Case | # Control |
| 1 | Tolerance | COGA | 1,110 | 2,024 | 3,348 | 3,958 |
| Yale-Penn | 1,192 | 818 | - | - | ||
| SAGE | 353 | 577 | 777 | 930 | ||
| OZALC | - | - | 2,274 | 1,071 | ||
| 2 | Withdrawal | COGA | 514 | 2,616 | 1,259 | 6,046 |
| Yale-Penn | 694 | 1,316 | - | - | ||
| SAGE | 200 | 730 | 257 | 1,451 | ||
| OZALC | - | - | 478 | 2,867 | ||
| 3 | Drinking more than intended | COGA | 1,317 | 1,817 | 3,826 | 3,480 |
| Yale-Penn | 1,525 | 485 | - | - | ||
| SAGE | 507 | 421 | 1,074 | 631 | ||
| OZALC | - | - | 2,055 | 1,290 | ||
| 4 | Desire to cut drinking | COGA | 1,436 | 1,701 | 2,896 | 4,413 |
| Yale-Penn | 1,411 | 599 | - | - | ||
| SAGE | 425 | 505 | 601 | 1,107 | ||
| OZALC | - | - | 1,420 | 1,925 | ||
| 5 | Giving up activities | COGA | 578 | 2,558 | 1,437 | 5,871 |
| Yale-Penn | 1,201 | 809 | - | - | ||
| SAGE | 215 | 715 | 274 | 1,434 | ||
| OZALC | - | - | 246 | 3,099 | ||
| 6 | Time spent drinking | COGA | 546 | 2,590 | 1,533 | 5,776 |
| Yale-Penn | 1,004 | 1,006 | - | - | ||
| SAGE | 251 | 679 | 354 | 1,354 | ||
| OZALC | - | - | 668 | 2,677 | ||
| 7 | Drinking despite problems | COGA | 784 | 2,351 | 2,163 | 5,144 |
| Yale-Penn | 989 | 1,021 | - | - | ||
| SAGE | 310 | 619 | 741 | 966 | ||
| OZALC | - | - | 1,180 | 2,165 | ||
1: Tolerance. Need for markedly increased amounts of alcohol to achieve intoxication or desired effect; or markedly diminished effect with continued use of the same amount of alcohol.
2: Withdrawal. The characteristic withdrawal syndrome for alcohol; or drinking (or using a closely related substance) to relieve or avoid withdrawal symptoms.
3: Drinking more than intended. Drinking in larger amounts or over a longer period than intended.
4: Desire to cut drinking. Persistent desire or one or more unsuccessful efforts to cut down or control drinking.
5: Giving up activities. Important social, occupational, or recreational activities given up or reduced because of drinking.
6: Time spent drinking. A great deal of time spent in activities necessary to obtain, to use, or to recover from the effects of drinking.
7: Drinking despite problems. Continued drinking despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to be caused or exacerbated by drinking.