. Author manuscript; available in PMC: 2020 Jul 1.

Published in final edited form as: Am J Ophthalmol. 2019 Mar 6;203:78–88. doi: 10.1016/j.ajo.2019.02.029

Table 5.

Effect of IOP on 3 Year ECD - among eyes with successful graft

	N=913	Mean (SD) (cells/mm²)	P-value

History of glaucoma/ Postoperative abnormal IOP at least 1 month following DSAEK			0.02

No/No	687	1689 (615)
Yes/No	41	1589 (676)
No/Yes	155	1733 (638)
Yes/Yes	30	1651 (692)

Early acute IOP event			0.48

No	904	1691 (625)
Yes	9	1630 (575)

IOP = intraocular pressure; ECD = endothelial cell density; DSAEK = Descemet stripping automated endothelial keratoplasty

^a.

Of 1330 study eyes, 913 had functioning grafts at 3 years with acceptable endothelial images

^b.

Model adjusted for CIARC determined preoperative ECD, PT, recipient diagnosis, donor history of diabetes, operative complications, and random surgeon and recipient effects

^c.

History of glaucoma defined as had glaucoma surgery, and/or on glaucoma medications

^d.

Postoperative abnormal IOP defined as had new glaucoma surgery, or put on new glaucoma meds without new glaucoma surgery, or had IOP >25 without any new glaucoma surgery or medications. (Eyes failed or censored within 1 month following DSAEK were eliminated). New glaucoma surgery performed included: laser trabeculoplasty (3 eyes) in 3 participants.

^e.

Early acute IOP defined as any occurrence of IOP>40 or paracentesis for pupillary block or angle closure in the first week post-operatively