Figure 1. Prolonged duration of loss of righting reflex by ethanol and other sedatives in Scn4b KO mice.
Effect of i.p. injections of (a) ethanol (3.6 g/kg, n = 6–8 per genotype per sex), (b) pentobarbital (50 mg/kg, n = 6–10 per genotype per sex), (c) ketamine (175 mg/kg, n = 6–9 per genotype per sex), or (d) gaboxadol (55 mg/kg, n = 8–9 per genotype per sex) on the duration of loss of righting reflex (LORR) in male and female WT and Scn4b KO mice.