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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Genes Brain Behav. 2019 May 2;18(6):e12562. doi: 10.1111/gbb.12562

Table 1. Physiological properties of CeA neurons from Scn4b KO and WT mice.

The membrane time constant was obtained by monoexponential fit of the initial part of the voltage responses under negative current steps. The voltage sag and afterdepolarization (ADP) values were plotted against the level of the injected current, and the corresponding relationships were fitted with linear functions. The slope of the linear fit is proportional with the magnitude of the voltage sag and ADP associated with the action of the intrinsic h-current.

Mice (number of cells) Resistance (MOhm) Capacitance (pF) Membrane Time Const. (ms) Voltage Sag Slope (mV/pA) ADP Slope (mV/pA) Rheobase (pA) Number of Spikes at Max Intensity Spike Threshold (mV)
WT
(n = 20)
502.9 ± 31.3 83.7 ± 6.9 30.4 ± 1.9 −0.08 ± 0.01 −0.10 ± 0.01 27.9 ± 2.8 6.0 ± 0.7 −41.6 ± 1.0
Scn4b KO
(n = 31)
520.2 ± 26.7 81.6 ± 5.2 30.6 ± 1.3 −0.08 ± 0.01 −0.10 ± 0.01 27.8 ± 2.2 6.1 ± 0.6 −43.1 ± 0.7