Table 3. No effect of Scn4b knockdown in the CeA on ethanol intake and preference.
Thirty days following microinjections of shScn4b-10, shScn4b-10, or a control shRNA into the CeA, mice underwent two 2BC drinking procedures using increasing ethanol concentrations of 0%, 5%, 10%, and 20% (v/v). There was a 4-week waiting period between the procedures. Data from both drinking procedures were combined (n = 10–12 mice per genotype).
Group | Ethanol (20%) Intake | Preference |
---|---|---|
shScn4b-268 | 13.5 ± 1.9 g/kg/24h | 0.43 ± 0.04 |
shScn4b-10 | 14.6 ± 1.0 g/kg/24h | 0.47 ± 0.03 |
Control | 14.8 ± 1.9 g/kg/24h | 0.47 ± 0.05 |