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. 2019 May 21;18(4):e12966. doi: 10.1111/acel.12966

Figure 1.

Figure 1

Time‐restricted feeding and exercise uniquely influence survival and body composition in aged, obese mice. (a) Schematic description of experimental mouse groups. (b) Mortality of aged mice during the 4‐month intervention phase. (c) Longitudinal mean body weight throughout the entire study. Total (d) body, (e) fat, and (f) lean mass in grams (g) at intervention onset (age 20 months; open circles) and endpoint (age 24 months, filled circles) are depicted (paired t‐tests) (n = 6–10) (p < *0.05,**0.01,***0.005) (ND‐SD = old, sedentary, ad libitum (AL) normal diet; FD‐SD = old, sedentary, AL fast‐food diet; FD‐TRF = old, sedentary, 8 hr dark cycle AL access to fast‐food diet; FD‐EX = old, voluntary running wheels, AL fast‐food diet)