Figure 2.

Exercise improves physical function and time‐restricted feeding improves nesting behavior in aged, obese mice. (a) Duration ran to exhaustion was assessed on a motorized treadmill test (ANOVA). (b) Nest quality was assessed at 1, 3, 5, and 24 hr in an activity of daily living behavioral test (two‐way ANOVA) (n = 5–10) (Mean ± SEM) (p < *0.05,**0.01,***0.005) (ND‐Y = young, sedentary, ad libitum normal diet; ND‐SD = old, sedentary, ad libitum normal diet; FD‐SD = old, sedentary, ad libitum fast‐food diet; FD‐TRF = old, sedentary, 8‐hr dark cycle ad libitum access to fast‐food diet; FD‐EX = old, voluntary running wheels, ad libitum fast‐food diet)