Table 3.
Significantly enriched KEGG pathway of DEGs in FA-vs-PM2.5–3H group.
| Pathway ID | Pathway Name | Gene Number | Rich Ratio | Q value |
|---|---|---|---|---|
| ko05410 | Hypertrophic cardiomyopathy (HCM) | 21 | 0.165354331 | 0.000145656 |
| ko05414 | Dilated cardiomyopathy (DCM) | 21 | 0.1640625 | 0.000145656 |
| ko04260 | Cardiac muscle contraction | 17 | 0.184782609 | 0.000195424 |
| ko03320 | PPAR signaling pathway | 18 | 0.153846154 | 0.001089685 |
| ko05144 | Malaria | 12 | 0.176470588 | 0.006066107 |
| ko04261 | Adrenergic signaling in cardiomyocytes | 22 | 0.114583333 | 0.008971435 |
| ko04510 | Focal adhesion | 32 | 0.09495549 | 0.01093564 |
| ko04964 | Proximal tubule bicarbonate reclamation | 7 | 0.25 | 0.011916956 |
| ko04974 | Protein digestion and absorption | 18 | 0.119205298 | 0.014059568 |
| ko05146 | Amoebiasis | 19 | 0.113095238 | 0.017217277 |
| ko04512 | ECM-receptor interaction | 17 | 0.114864865 | 0.025215623 |
| ko04010 | MAPK signaling pathway | 33 | 0.084398977 | 0.033563343 |
| ko04911 | Insulin secretion | 13 | 0.12745098 | 0.033563343 |
| ko04972 | Pancreatic secretion | 15 | 0.11627907 | 0.033563343 |
| ko05412 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 13 | 0.125 | 0.033563343 |
| ko00010 | Glycolysis/Gluconeogenesis | 12 | 0.129032258 | 0.035681392 |
| ko04920 | Adipocytokine signaling pathway | 12 | 0.127659574 | 0.03683053 |