Figure 5.
Evaluation of Targeting and Therapeutic Effects of 3WJ/CD133apt/Anti-miR21 Nanoparticles in an Animal Trial
(A) Fluorescence image showing RNA nanoparticle distribution in organs at 8 h post-injection. (B) TNBC tumor growth curve over the course of 5 injections. Data are represented as mean ± SEM. *p < 0.05. (C) qRT-PCR assay to study downstream gene expression level at the mRNA level. Data are represented as mean ± SD. **p < 0.01. (D) Western blot assay to study downstream gene expression at the protein level. (E) Immunohistochemistry assay demonstrating Act-caspase3 level in tumor.