Table 1.
Samples | AF4 |
ChimeRScope | STAR-Fusion | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Targeted |
De novo
|
||||||||||
Length (bp) | Coverage | TP | FP | FN | F-score | TP | FP | FN | F-score | F-score | F-score |
50 | 5× | 146 | 0 | 4 | 0.986 | 143 | 1 | 7 | 0.973 | 0.948 | 0.416 |
50 | 20× | 147 | 0 | 3 | 0.990 | 144 | 2 | 6 | 0.973 | 0.954 | 0.855 |
50 | 50× | 147 | 0 | 3 | 0.990 | 144 | 2 | 6 | 0.973 | 0.947 | 0.867 |
50 | 100× | 147 | 0 | 3 | 0.990 | 144 | 3 | 6 | 0.970 | 0.908 | 0.868 |
50 | 200× | 147 | 0 | 3 | 0.990 | 144 | 3 | 6 | 0.970 | 0.905 | 0.875 |
75 | 5× | 144 | 0 | 6 | 0.980 | 141 | 1 | 9 | 0.966 | 0.948 | 0.700 |
75 | 20× | 147 | 0 | 3 | 0.990 | 143 | 1 | 7 | 0.973 | 0.949 | 0.865 |
75 | 50× | 147 | 0 | 3 | 0.990 | 143 | 1 | 7 | 0.973 | 0.957 | 0.872 |
75 | 100× | 147 | 0 | 3 | 0.990 | 144 | 2 | 6 | 0.973 | 0.954 | 0.875 |
75 | 200× | 147 | 0 | 3 | 0.990 | 144 | 3 | 6 | 0.970 | 0.947 | 0.875 |
100 | 5× | 144 | 0 | 6 | 0.980 | 140 | 0 | 10 | 0.966 | 0.940 | 0.692 |
100 | 20× | 147 | 0 | 3 | 0.990 | 143 | 1 | 7 | 0.973 | 0.957 | 0.878 |
100 | 50× | 147 | 0 | 3 | 0.990 | 143 | 1 | 7 | 0.973 | 0.957 | 0.875 |
100 | 100× | 147 | 0 | 3 | 0.990 | 143 | 1 | 7 | 0.973 | 0.957 | 0.872 |
100 | 200× | 147 | 0 | 3 | 0.990 | 143 | 1 | 7 | 0.973 | 0.957 | 0.877 |
Note: Each dataset contains fused reads of 150 gene pairs. In the targeted mode, the names of the 655 target gene pairs (including all 150 target ones) are given in the command line, along with the transcriptome. In the de novo mode, only the transcriptome is given.