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. 2019 Jul 5;35(14):i225–i232. doi: 10.1093/bioinformatics/btz346

Table 1.

AF4 for simulated datasets (Liu et al., 2016)

Samples AF4
ChimeRScope STAR-Fusion
Targeted
De novo
Length (bp) Coverage TP FP FN F-score TP FP FN F-score F-score F-score
50 146 0 4 0.986 143 1 7 0.973 0.948 0.416
50 20× 147 0 3 0.990 144 2 6 0.973 0.954 0.855
50 50× 147 0 3 0.990 144 2 6 0.973 0.947 0.867
50 100× 147 0 3 0.990 144 3 6 0.970 0.908 0.868
50 200× 147 0 3 0.990 144 3 6 0.970 0.905 0.875
75 144 0 6 0.980 141 1 9 0.966 0.948 0.700
75 20× 147 0 3 0.990 143 1 7 0.973 0.949 0.865
75 50× 147 0 3 0.990 143 1 7 0.973 0.957 0.872
75 100× 147 0 3 0.990 144 2 6 0.973 0.954 0.875
75 200× 147 0 3 0.990 144 3 6 0.970 0.947 0.875
100 144 0 6 0.980 140 0 10 0.966 0.940 0.692
100 20× 147 0 3 0.990 143 1 7 0.973 0.957 0.878
100 50× 147 0 3 0.990 143 1 7 0.973 0.957 0.875
100 100× 147 0 3 0.990 143 1 7 0.973 0.957 0.872
100 200× 147 0 3 0.990 143 1 7 0.973 0.957 0.877

Note: Each dataset contains fused reads of 150 gene pairs. In the targeted mode, the names of the 655 target gene pairs (including all 150 target ones) are given in the command line, along with the transcriptome. In the de novo mode, only the transcriptome is given.