Table 2.
Results of AF4 and STAR-Fusion on cfRNA data
| Samples | #readpairs (millions) | Coverage | Number of TMPRSS2-ETV4/ERG supporting fragments |
Number of reported fusion events |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF4 |
STAR-Fusion |
AF4 |
STAR-Fusion |
|||||||||
| Targeted |
De novo
|
Targeted | De novo | |||||||||
| Final | Prelim | Final | Prelim | Final | Prelim | Final | Prelim | |||||
| Prc101 | 373.8 | 29 132 | 19 | 345 | 19 | 345 | 0 | 31 | 9 | 239 | 19 | 979 |
| Prc108 | 464.5 | 36 200 | 9 | 114 | 0 | 116 | 0 | 13 | 12 | 140 | 13 | 787 |
| HC118 | 399.8 | 31 158 | — | — | — | — | — | — | 1 | 289 | 5 | 930 |
| HC160 | 348.9 | 27 191 | — | — | — | — | — | — | 0 | 303 | 21 | 254 |
| HC332 | 443.2 | 34 540 | — | — | — | — | — | — | 1 | 350 | 18 | 840 |
Note: The coverage is calculated by the formula #readpairs × 166/2.13, where 2.13 (million bp) is the panel size and 166 (bp) is used as the average fragment length. The middle section of the table shows the number of readpairs that support either the TMPRSS2-ETV4 or the TMPRSS2-ERG fusion event. As these two fusions are not expected in the healthy controls, they are marked by ‘—’. The right most part of the table shows the number of unique fusion events reported.