Fig. 2.

Comparison of GkmExplain, ISM, deltaSVM and SHAP on an individual simulated sequence. An SVM with a gkmrbf kernel with l = 6, k = 5 and d = 1 was used to distinguish sequences containing both TAL1 and GATA1 motifs from sequences containing only one kind of motif or neither kind of motif. The locations of embedded GATA1 motifs are indicated by blue stars, and the location of the embedded TAL1 motif is indicated by a red star. The relatively poor performance of ISM and deltaSVM is due to the nonlinear nature of the RBF kernel