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. 2019 Jul 5;35(14):i4–i12. doi: 10.1093/bioinformatics/btz348

Fig. 9.

Fig. 9.

Batch Effect removal workflow estimates the inclination toward G1/S cell cycle phase by combining Marker Genes and Score Cells. The Batch Effect Removal reports 43% of genes are significantly correlated with the derived cell cycle phase estimator. After removing this source of variance, the PCA plot is not confounded by cell cycle phase