Table 2. .

The Associations of HIV Monoinfection and HIV/HCV Coinfection With FIB-4 in the Total Cohort (n = 137) in Multivariable Models Adjusted for Demographic, Lifestyle, Metabolic Factors, and Kyn/Trp Ratio

	Adjusted Modela		Adjusted Model With Kyn/Trp Ratiob
Variables	% Effect (95% CI)	P Value	% Effect (95% CI)	P Value
HIV monoinfection	37 (9 to 73)	.008	29 (2 to 63)	.035
HIV/HCV coinfection	164 (100 to 250)	<.001	123 (63 to 203)	<.001
Kyn/trp ratio	N/A	N/A	27 (5 to 53)	.013

Abbreviations: CI, confidence interval; FIB-4, fibrosis-4 score; HCV, hepatitis C virus; IDU, injection drug use; kyn/trp ratio, kynurenine:tryptophan ratio; VAT, visceral adipose tissue.

^aAdjusted for age, race, alcohol, marijuana, IDU, steatosis, and VAT, in addition to the factors listed above.

^bAdjusted for kyn/trp ratio, plus all factors in previous model.